Evidence-Based Alternative Approaches to Migraine Prevention in Children: Riboflavin, Magnesium, Coenzyme Q10, Vitamin D, Feverfew, and Butterbur

Migraine is a common neurological condition in children, often resulting in significant morbidity and impaired quality of life. Traditional pharmacological treatments are widely used, but there is increasing interest in complementary and alternative approaches. This article reviews evidence supporting the use of riboflavin, magnesium, coenzyme Q10 (CoQ10), feverfew, and butterbur for preventing migraines in pediatric patients.

Summary of Evidence for Riboflavin in Pediatric Migraine

Riboflavin (Vitamin B2) has emerged as a potential preventive treatment for migraines, including in pediatric populations. Here’s a summary of the current evidence regarding its efficacy and safety for treating migraines in children:

Summary of Evidence for Magnesium in Pediatric Migraine

Magnesium is an essential mineral that has garnered attention for its potential role in preventing migraines, including in pediatric populations. Here’s a summary of the current evidence regarding its efficacy and safety for treating migraines in children:

Summary of Evidence for Coenzyme Q10 in Pediatric Migraine

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant that has been investigated for its potential role in preventing migraines, including in pediatric populations. Here’s a summary of the current evidence regarding its efficacy and safety for treating migraines in children:

Summary of Evidence for FeverFew in Pediatric Migraine

Feverfew (Tanacetum parthenium) is a herbal remedy traditionally used for migraine prevention, and its use in pediatric migraine management has garnered interest. The evidence surrounding feverfew for migraines in children is still evolving, but here are some key points from recent studies

Summary of Evidence for Vitamin D in Pediatric Migraine

Vitamin D, often referred to as the “sunshine vitamin,” is a fat-soluble vitamin crucial for calcium absorption, bone health, and immune function. In recent years, emerging evidence has suggested that vitamin D may also play a role in preventing migraines, including in pediatric populations. This summary provides an overview of the current evidence on the use of vitamin D for preventing migraines in children.

Conclusion

In conclusion, riboflavin, magnesium, coenzyme Q10, and Vitamin D are the most promising options for preventing pediatric migraines, particularly due to their favorable safety profiles. Despite mixed data, these treatments may yield positive outcomes, making them appealing alternatives for families seeking non-pharmacologic solutions to manage their child’s migraines. While feverfew and butterbur offer potential benefits, their lack of evidence and safety profiles render them less desirable options.

Other Resources:

Texas Children’s Hospital: Dietary Supplements and Nutraceuticals for Children with MIgraines